Lung SBRT through Radiobiology

Lung SBRT through Radiobiology

Purpose: Stereotactic body radiation therapy (SBRT) has emerged as a standard treatment modality for medically inoperable early-stage lung cancer patients. The aim of this paper is to calculate radiobiological parameters for a sample of 39 patients who underwent lung SBRT. Materials and Methods: For SBRT, a typical regimen of 50 Gy in 4 5 fractions results in local tumor control rates around 99...

Abdominal compression during lung SBRT

The tumor radiobiology of SRS and SBRT: are more than the 5 Rs involved?

Stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT), also known as stereotactic ablative radiation therapy (SABR), are rapidly becoming accepted practice for the radiation therapy of certain tumors. Typically, SRS and SBRT involve the delivery of 1 or a few large-dose fractions of 8 to 30 Gy per fraction: a major paradigm shift from radiation therapy practice over the...

Salvage SBRT for Previously Irradiated Lung Cancer

Purpose: Patients with locally recurrent lung cancer after definitive radiation therapy pose a challenge in management. Surgery is often not an option and chemotherapy offers poor long-term local control. Stereotactic body radiotherapy (SBRT) was investigated in an attempt to salvage locally recurrent lung cancer. Materials and Methods: From March, 2009 to January, 2010, 8 patients who had prev...

Adaptive Stereotactic-body Radiation Therapy (SBRT) Planning for Lung Cancer Significance and Innovation: Tumor shrinkage during SBRT of lung cancer

Introduction: SBRT is an emerging radiotherapy technique for treating early-stage non-small cell lung cancers (NSCLC) or oligometastatic lesions to the lung [3, 4]. Significant tumor shrinkage has been observed in some patients during the course of SBRT [1, 2]. Adaptive planning has the potential to reduce radiation dose to organs of risk (OARs), and further escalate radiation dose to the tumor...